These articles are a bit more clear & contain info that is important. According to them, 4:4:4 10-bit was added with SDK 12.2 (2024) & 4:2:2 10-bit was added with SDK 13.0 (2025).
NVIDIA Video Codec SDK provides a comprehensive set of APIs for hardware-accelerated video encode and decode on Windows and Linux. The 12.2 release improves video quality for high-efficiency video…
developer.nvidia.com
The release of NVIDIA Video Codec SDK 13.0 marks a significant upgrade, adding support for the latest-generation NVIDIA Blackwell GPUs. This version brings a wealth of improvements aimed at elevating…
developer.nvidia.com
Higher bit-depth encoding enhancement
NVIDIA Video Codec SDK 13.0 introduces 10-bit encoding support in H.264 on NVIDIA Blackwell GPUs. All the chroma subsampling formats—4:2:0, 4:2:2 and 4:4:4—support encoding 10-bit content.
In addition, NVIDIA Blackwell NVENC can encode 8-bit content as 10-bit for H.264 and HEVC, a feature already available for AV1 in ADA.
ADA and earlier GPUs continue to support this feature for HEVC, but unlike NVIDIA Blackwell, the input YUV is upscaled from 8- to 10-bit as a preprocessing step using CUDA.
This feature improves the coding efficiency due to higher precision in the encoding pipeline. This upgrade results in smoother gradations and more accurate color reproduction, ideal for high-quality video production. Many of the input-related calculations in the encoder are done in 10-bit instead of 8-bit. Applications can expect an improvement of around 3% in compression efficiency when using this feature without any significant impact on encoder performance.
Unlike AV1, 10-bit encoding is supported only on select profiles for H.264 and HEVC. Applications should only enable this feature if the decoder supports 10-bit profiles.